MatthewDean

MatthewDean

MatthewDean

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NAC vs. Glutathione supplements - NAC works to raise GSH levels far better than oral glutathione supplements primarily because reduced glutathione is an endogenous antioxidant that is best produced by the body from raw materials: the amino acids L-cysteine, glutamic acid, and glycine. 2 of the 3, L-cysteine and glycine, are rate-limiting nutrients for GSH production. NAC, or N-acetyl-L-cysteine, provides your body with valuable L-cysteine to increase glutathione production. Glycine is also valuable in this equation. The body synthesizes GSH in a two-part process: 1) L-cysteine links with glutamic acid by means of glutamate cysteine ligase, resulting in gamma-glutamylcysteine (GGC); 2) glycine is attached by means of glutathione synthase. Research has shown that GGC converts to 5-L-oxoproline and is excreted in the urine when there is not enough glycine available to complete the transition to GSH.

Links:
N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/

Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855430/

Brain Derived Neurotrophic Factor levels can be increased with the right supplements. In this video we discuss DHA from fish/krill oil, lion's mane mushroom, curcumin from turmeric, and coffee berry/coffee fruit extract.

DHA/BDNF study link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778907/

Coffee fruit / BDNF study link:
https://pubmed.ncbi.nlm.nih.gov/23312069/

Photos
Mushrooms – Photo by Gina Sell on Unsplash
Fish – Photo by Diane Helentjaris on Unsplash
Turmeric – Photo by FOODISM360 on Unsplash
Coffee fruit – Image by Daniel Ramirez from Pixabay

PUFA oils are vegetable/cooking oils that are high in the polyunsaturated Omega 6 linoleic acid. In this video I detail why you should never cook with oils that are high in polyunsaturated fatty acids, how to tell if a cooking oil is good for you based on its fatty acid composition, which specific cooking oils you should never consume under any circumstances, which ones are ok sparingly, and which cooking oils/fats you can safely use all the time for good health.

Saturated fat meta analysis link:
https://www.bmj.com/content/351/bmj.h3978

Brain Derived Neurotrophic Factor, also known as abrineurin, is a peptide molecule found in the brain (hippocampus, cortex, and basal forebrain) and spinal cord. It is part of the neurotrophin family of growth factors which include NG-3, NG-4, and Nerve Growth Factor.
BDNF has been intensely studied since it was first isolated in 1982, but we still have a lot more to learn. From what we now know, the primary role of BDNF is to maintain the lifespan of neurons (brain cells), and for this reason is thought to play a crucial role in long term memory and overall cognitive function. It also plays a role in neurogenesis and synaptogenesis – the creation of brain cells and brain cell pathways – indicating a central role in learning and higher thinking.

Ways to Produce More Include:
1) Intense Exercise
2) Exposure to Sunlight
3) Social Engagement
4) Listening to Music
5) Meditation

Seasonal Variation of Serum BDNF research:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487856/

Social Engagement - Photo by Kevin Curtis on Unsplash
Sunlight - Photo by Ainsley Myles on Unsplash
Sprinting - Photo by Jonathan Chng on Unsplash
Meditation - Photo by Simon Migaj on Unsplash
Listening to Music - Photo by Element5 Digital on Unsplash

Magnesium l-threonate is one the most effective supplements to increase your brain's magnesium levels, which can help address better learning and memory, headaches, anxiety, and depression, among many other issues. It has been shown in clinical studies to increase overall cognitive ability, cognitive fluctuation, brain age, synaptic density, and brain plasticity.

Study link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927823/

Antarctic Krill Oil goes beyond fish oils to provide superior nutrition and bioavailability. It's unique synergistic combination of Omega 3 fatty acids, phospholipids, and antioxidants is unmatched when it comes to providing fuel your brain and body.

"Metabolic Effects of Krill Oil are Essentially Similar to Those of Fish Oil but at Lower Dose of EPA and DHA, in Healthy Volunteers" STUDY LINK:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024511/

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Created 2 months, 2 weeks ago.

6 videos

Category Health & Medical

In this channel we explore brain health optimization techniques that include nutrients, supplements, natural nootropics, lifestyle activities, toxins, ketosis, fasting, etc. Join us to keep your brain strong, sharp, and clear.