In the film, director Jones reveals an alleged eugenics-obsessed group of global elite whose mission is the elimination of most of the Earth’s population and the enslavement of the rest. He makes claims of a Satanic international network "steering planetary affairs for hundreds of years..." He discusses his claims about the pseudo-science eugenics being used by governments, Microsoft and the band U2.

The film presents the conspiracy theory that American presidents since the 1960s have served as "front men" for entities such as the Council on Foreign Relations, Trilateral Commission, Bilderberg Group, Wall Street banks, the Federal Reserve, the Military-industrial complex, Mossad, and others, arguing that multinational corporations and powerful elite families, such as the Rothschild family and Rockefeller family hold the real "power behind the throne." The film claims the main motive of these groups is to set up a New World Order where offshore banks subversively engage in looting of the wealth of the American people. The film primarily focuses on American president Barack Obama and his actions during his young presidency. However, Jones also discusses John F. Kennedy, whom he insinuates was assassinated by these oligarchs for attempting to end the Vietnam War and abolish the Federal Reserve, and labels as the "last true President of the United States". He also discusses George H. W. Bush, and the George W. Bush administration.

The film claims that Obama has been carefully installed by powerful elite families, and that he is deliberately working against the best interests of the American people. It discusses and references mainstream news pieces to suggest that elite families and multinational institutions utilize Obama in an effort to con the American people into accepting their globalist agenda, which, according to Jones, would include items such as forced national service, warrantless wiretapping, Federal Emergency Management Agency (FEMA) concentration camps, martial law, and a Bank of the World, which would dominate America through carbon taxes.