For many, the Resident Evil saga was their first approach to the zombie genre, marking several generations since childhood. It introduces the concept of an undead pandemic caused by the "accidental" release of a virus, the development of biological weapons, the fall of a society, the need and urgency to find a cure that in almost all cases comes in the form of a vaccine, the escape from a city, and the guarantee of a "new dawn" as can be seen in the end of the first 4 games.
Resident Evil 4 gave a fundamental change to the saga, omitting the modifications in the gameplay with respect to its predecessors, now the enemies were not the classic clumsy, slow, and disorganized zombies, but people who retained certain of their "human" qualities, both physical and mental, which gave them the ability to organize, communicate, apply tactics and act together.
Also, now the villain was not an agent of a pharmaceutical company, but a member of a cult with satanic tinges coincidentally called "Los Iluminados", being a direct reference to what we know as “The Illuminati", which, in turn , we can easily associate with Freemasons. Why include them in a video game?
The thing does not end there, now those "infected" with "las plagas" (which translates as plague = disease) received a particular name "ganados", which translated means cattle, and only by making the connection between who was their leader, we can deduce that this is a reference to the "goyim" or "gentiles" from the “Protocols of the learned elders of Zion”, that it refers to all non-Jews and that it is used in a derogatory way to describe them as "cattle."
So here “los iluminados” aka the illuminati, resurrected the plagues and infected the cattle (goyim) through injections to convert them to their cult, manipulate them remotely, seize their will and use them as an army, as sacrificial pawns. As a side effect, the infected became hostile, aggressive, violent, and bloodthirsty.
I believe that it is a clear and direct reference to what they expect with the vaccine, to apply it to all the "goyim" and to seize their will.
Why do they show us so many cases of "entertainment" where for one reason or another those involved had to receive an injection or something similar and that had negative repercussions or an undeclared double intention? There are too many cases to be "coincidence." I am of the idea that they all show us a glimpse of what they are looking for with current injections: mind control, heart attacks, reducing certain population subgroups, altering reproduction and fertility, changing moods, genetically modifying people, creating a dependency / addiction at higher doses, altering the psyche, facilitating the transition to transhumanism or a more technologically advanced control system, generating new diseases or mutations that will eventually justify new genetic treatments and more experimentation.
References:
• Resident Evil 4 files narrated (used: “Our Mission”): https://www.youtube.com/watch?v=CPeJTcRYis8
• Resident Evil 4 all files (key ones: Capture Luis Sera, Castellan Memo, Butler’s Memo, Luis Memo 2, Luis Memo 3, Luis Memo 4, Our Mission): https://www.youtube.com/watch?v=lypBwtdZEN8
• Resident Evil 4 Radio Conversations: https://www.youtube.com/watch?v=SxHnOYC2SpQ&t=12s
• About the plagas: https://residentevil.fandom.com/wiki/Plaga
• About the iluminados: https://residentevil.fandom.com/wiki/Los_Iluminados
• About the ganados: https://residentevil.fandom.com/wiki/Ganado
Cutscenes used:
• Saved by the bell: https://www.youtube.com/watch?v=9cSwCBrtdtU&list=PL81F7D9BEF436D882&index=7
• Conversation: https://www.youtube.com/watch?v=qnm32t3o7cQ&list=PL81F7D9BEF436D882&index=9
• Nightmare: https://www.youtube.com/watch?v=y_wVepxkgN0&list=PL81F7D9BEF436D882&index=16
