JF Gariépy - NEURO.tv Episode 4 -The Evolution of the Synapse

NEURO.tv Episode 4 -The Evolution of the Synapse

Jean-Francois Gariépy
Published on Aug 31, 2013
In this episode, we look at the extraordinary evolutionary history of the genes related to the synapse which were present even before the evolution of neurons. Guest: Kenneth S. Kosik, UCSB.

neuro.tv http://archive.is/ibwfz

Participants from left to right: Jean-François Gariépy, John Kubie, Kenneth S. Kosik, Leanne Boucher and Steven Miller.

"1:20" The importance of evolution.
"2:53" What is an animal?
"8:41" What is the difference between a colony and an animal?
"13:29" The Cambrian explosion.
"16:29" The diversity of non-bilaterians.
"21:34" The rudiments of a nervous system.
"28:24" Genes related to the synapse are already present in sponges.
"32:52" In situ hybridization reveals the RNA produced from genes.
"41:42" A highly-conserved protein.
"53:07" Genes turned on and off together during development.
"1:09:31" How nervous systems opened a new ecological niche for animals.

http://blog.brainfacts.org/404?item=%2f2013%2f08%2fneuro-tv-episode-4-the-evolution-of-the-synapse%2f&user=extranet%5cAnonymous&site=brainfacts

Many thanks to our guests! Here is the PNAS paper:

Conaco C, Bassett DS, Zhou H, Arcila ML, Degnan SM, Degnan BM, Kosik KS (2012) Functionalization of a protosynaptic gene expression network. 109 Suppl 1:10612-10618 https://www.ncbi.nlm.nih.gov/pubmed/22723359

Some Wikipedia reading:

https://en.wikipedia.org/wiki/Regulation_of_gene_expression

Kenneth's UCSB homepage: https://www.mcdb.ucsb.edu/people/faculty/kosik
Leanne's twitter: http://twitter.com/BoucherLeanne
John's blog: http://coronaradiata.net/
Steven's blog: http://neurosciencedc.blogspot.com/
Jean-Francois' twitter: http://twitter.com/JFGariepy

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