Human cloning is real

The prominent scientific journal Cell published a paper by scientists at Oregon Health & Science University announcing that they had successfully derived stem cell lines from cloned human embryos. Some context is necessary, however, to start to grasp the implications of what has taken place.

First of all, a brief primer to the science. Cloning is more commonly referred to in scientific circles as “somatic cell nuclear transfer (SCNT),” where scientists take the DNA from an adult (somatic) cell and transfer it into an unfertilized egg, which has had its own DNA removed. Normally to begin developing into an embryo, a fetus, and ultimately an adult human being, the egg has to be fertilized by a sperm to which kick off the series of coordinated steps that constitute human development.

Instead of having the genetic material from two parents combine into a unique new life, however, cloning takes the full genetic information from an adult and places it into the emptied egg. These researchers immersed the egg in a caffeine solution and delivered regular electrical shocks, among other techniques, forcing it to enter development, dividing and growing until it reached “blastocyst” stage, where a protective outer layer called the trophoblast surrounds the mass of inner cells (ICM) that will constitute the myriad parts of a human body, and being.

At this point, as is the necessary procedure to obtain embryonic stem cells, they dissolved that protective outer layer to obtain the inner cells rich in total potential, and grew them into an “immortal” line of stem cells. To prove their success, some of those cells were programmed into muscle cells and grown into tumors under the skin of immune-suppressed mice. The muscle cells were made to contract, and filmed doing so.

The controversies and debates about cloning specifically are legion, and will be given new intensity with this announcement, but some points can be made at the outset.