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https://www.testosterone.me/men-with-low-testosterone-found-more-likely-to-die-from-covid-19
As if getting the Coronavirus wasn't bad enough, especially if you're in the high-risk category already (high blood pressure, heart disease, smoker, respiratory issues or over 60 years old), now a German hospital has discovered that their male patients with low testosterone are succumbing to the virus's fatal attack more than their peers with normal testosterone levels.
Since the beginning of the pandemic, the data collected on patients has revealed that men are twice as likely to die from COVID-19 as compared to women. The effect of low testosterone on men may be the reason behind this statistic.
Testosterone and the Male Immune System
Testosterone does not just play a role in a man's sexual health, as many people tend to think. This is a hormone that plays a role in many different processes and systems within the human body. One of these is the immune system, where testosterone plays an immunomodulatory role.
The hormone has been observed modulating T-cell activation, and a 2016 study found that testosterone is associated with cytokine responses and mediates the body's response to various infections. Cytokines are tiny proteins that are secreted by certain cells of the immune system and are an essential part of cellular communication during an immune response to infection.
They travel to the site of infection and signal the body to send more immune cells to attack the infectious agent.
Cytokine Storm Causes Respiratory Failure in Patients
The scientists studying this new virus highly suspect that death is mainly brought on by a “cytokine storm.” Cytokines are essential components of our immune system, but when they begin to get out of control, it causes significant damage to the body. All of the immune cells arriving at the site (in the case of COVID-19, the site is the lungs) cause inflammation, and healthy cells can be attacked in all the confusion.
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