https://www.testosterone.me/both-high-and-low-levels-of-testosterone-correlate-with-cardiovascular-issues-in-men
As men age, hormone levels tend to decline or become imbalanced. The majority of hormones tend to decrease, but occasionally levels are seen to be too high. For example, this includes testosterone, growth hormone, thyroid stimulating hormone (TSH), etc. All of these hormones (and more!) play essential roles in our bodies – roles that need to be continued if one wants to live a long and happy life. A hormone of major interest to most men is testosterone.
As men age, testosterone tends to decline by about 10% a decade after he reaches 30 years of age. Unfortunately, we are seeing low levels happening even earlier in men due to poor lifestyle choices and environmental factors, most likely. A recent study has found that if a man’s testosterone levels are out of balance, being too low or even too high, he is at increased risk for cardiovascular issues.
Low Testosterone a Risk Marker for Hypertension
The results of a recent study, published in the Journal of the American Heart Association, demonstrated that high blood pressure (hypertension) is associated with decreased free testosterone, total testosterone and sex hormone-binding globulin (SHBG) in middle-aged and older men.
Free testosterone is the testosterone in the blood that is not attached to other molecules or proteins. It just the testosterone molecule itself circulating through the bloodstream. It is bioavailable and free to use by the body. Total testosterone includes both the unbound (free) testosterone and the testosterone that is bound to proteins, such as SHBG or albumin. The bound testosterone cannot enter most cells of the body.
SHBG is a protein that is made by the liver. It chemically binds to sex hormones in both men and women and carries the hormones through the bloodstream. Its role is to control the amount of testosterone that the body uses.
For years, there has been controversy regarding whether or not high testosterone causes cardiovascular (CV) issues, especially increased heart attack risk. The results of multiple studies were inconclusive and contradictory. Researchers in China wanted to try again and attempt to discover the relationship between testosterone levels and cardiovascular events.
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