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Vioxx: The Case of the Deadly Data Analysis

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First published at 06:35 UTC on February 19th, 2020.

MathematicalSoftware

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Vioxx was a deadly painkiller marketed between 1999 and 2004 as a super-aspirin much safer and much more expensive than aspirin and other traditional painkillers. In fact it greatly increased the risk of death from heart attack and stroke.

This v…

This video is a case study on the remarkably flawed data analysis used for FDA approval of Vioxx. It is taken from a longer presentation to the Caltech Alumni Entrepreneurship Group in Palo Alto on automating data analysis to reduce the risk of such costly disasters.

Please note:

The presenter is not a qualified medical professional. Nothing in this video, specifically including the Vioxx case study, is intended as medical or legal advice and should not be treated as such. If you have a medical, legal, or other issue or concern that requires qualified professional advice such as a medical condition, you should get advice from a properly qualified professional such as a licensed medical doctor or attorney.

A written version of the Vioxx Case Study is found on page 14 and following pages of this white paper: http://wordpress.jmcgowan.com/wp/wp-content/uploads/2017/06/Automating-Complex-Data-Analysis-White-Paper.pdf

The white paper includes footnotes and references.

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