The Unearthly 1957

The Unearthly is a 1957 independently made American black-and-white science fiction horror film, produced and directed by Boris Petroff (as Brook L. Peters). It stars John Carradine, Myron Healey, Allison Hayes, Marilyn Buferd, Arthur Batanides, Sally Todd, and Tor Johnson. The film was written by Jane Mann and John D.F. Black.
At his psychiatric institute, Dr. Charles Conway (John Carradine) is surreptitiously experimenting with artificial glands to try to create longevity; he works with his minion Lobo (Tor Johnson) and his assistant Dr. Sharon Gilchrist (Marilyn Buferd). Conway receives his test subjects through an associate, Dr. Loren Wright (Roy Gordon), who delivers patients seeking treatment for lesser conditions. After this, they are then taken into the operating room for Conway's illicit surgery.
Wright delivers his newest find, Grace Thomas (Allison Hayes), who is seeking treatment for depression. When Conway balks at Wright for bringing him a patient with living relatives, he confides in Conway that he plans to throw Grace's purse and bags into the bay, to fool family and the authorities into believing she had committed suicide. He then asks Conway for a demonstration of his experimental progress; Conway takes him down into the basement, where he introduces him to Harry Jedrow (Harry Fleer), his latest victim. Jedrow is clearly alive, but severely disfigured and in a vegetative state; this concerns Wright, who reveals that Jedrow's sister is currently seeking him out. Conway is furious, since none of his patients were supposed to have ties of any kind.
That night, Lobo (who famously delivers the line "Time for go to bed!") discovers Frank Scott (Myron Healey) roaming around the grounds. Scott attempts to conceal his identity, but Conway quickly deduces that he is an escaped convict from his description in the newspapers, as well as a telltale tattoo on his wrist. Rather than turn Scott into the police, he offers him the chance to take part in his experiments. Knowing the odds are stacked against him, Scott accepts his offer.
Scott is introduced to Grace the following morning, along with the two other patients: Danny Green (Arthur Batanides), who is being treated for anger issues, and pretty young Natalie Andries (Sally Todd), whose treatment schedule for a nervous breakdown is nearing completion. After demanding Wright to make out a certificate of death for Harry Jedrow, Conway happily informs Natalie that one last treatment for her is all that's necessary. While the other patients sleep, Natalie is sedated, taken to the operating room, and given an artificial gland along with a high dosage of electricity. The procedure backfires, and she ends up a senile old woman. They hide her in a back room.
Lobo is ordered to bury Jedrow alive, but Frank Scott sneaks out to the burial site and opens the coffin. Jedrow rises out of it and escapes, and Lobo - not having been alerted - buries the casket. Sharon confronts Conway about his etc...