2015 Steelers 43 vs 49ers 18

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Big Ben is nearly perfect, hitting 21 of 27 for 369 yds and 3 TDs, DeAngelo Williams ties a team record with 3 rushing TDs and Antonio Brown shreds the Niners secondary with 9 catches for 195 yds and a TD. The explosive Steeler offense scores early and often and even convert a pair of early 2-point tries, undeterred by the absence of starters LeVeon Bell and Martavis Bryant (out due to substance abuse violations). Ryan Shazier tallies a career-high 15 tackles and 1 of Pittsburgh's 5 sacks of Colin Kaepernick. Despite moving the ball well at times, the Niners fail to covert yards into points as drives of 17 and 18 plays net only 3 points.