#02: Zero-Carb | Ketogenic | Carnivore Diet Critique with Ex-Carnivore Kyle Mamounis

00:00 - Music
04:42 - Introduction
06:22 - Kyle's brief background
07:36 - Defining of terms (e.g., zero-carb, carnivore, raw primal)
08:53 - Danny's motivation for talking to Kyle
10:25 - Super chats donated to Ray Peat and please block people in the chat if they're bugging you
11:10 - Kyle's background proper
19:26 - The raw paleo forum and eating raw meat
23:06 - When Kyle met Lex Rooker: https://zerocarbzen.com/2016/05/04/lex-rooker-the-unique-healing-power-of-an-all-raw-zero-carb-diet/
26:50 - Kyle's work with The Ancestral Health Symposium
29:20 - Mamounis, Kyle J. (2017) "The Dangers of Fat Metabolism and PUFA: Why You Don’t Want to be a Fat Burner," Journal of Evolution and Health: Vol. 2: Iss. 1, Article 9. https://jevohealth.com/journal/vol2/iss1/9/
29:45 - Kyle's transition away from the low-carb worldview
34:55 - Vindicating sugar for the historical record
27:23 - Danny's struggle with cognitive dissonance on the pro-obesity effects of sugar
40:15 - Who's more "scientific" carnivores or vegans?
43:18 - "As information about the many physiological and biochemical events associated with diabetes has accumulated, the basic doctrine that "sugar causes diabetes" has extended itself to whatever the topic of discussion is: "Glucose causes" the death of beta-cells, glucose causes blood vessels to become leaky, glucose causes cells to be unable to absorb glucose, glucose causes the formation of free radicals, glucose impairs immunity and wound healing, but causes inflammation while preventing the "respiratory burst" in which free radicals are produced by cells that cause inflammation, it disturbs enzyme functions, impairs nerve conduction and muscle strength, etc., and it is also addictive, causing people to irrationally seek the very material that is poisoning them." http://raypeat.com/articles/articles/glucose-sucrose-diabetes.shtml
44:20 - Entering the fat burning state
51:20 - Gluconeogenesis - "For non-ketotic low carb dieting, this energy substrate production may account for much of the observed weight loss; the process of gluconeogenesis from amino acids costs approximately 33% of the energy obtained in the oxidation of the resulting glucose [12]. Additionally, if the saturable urea system [13] is overwhelmed by amino acid derived ammonia, symptoms of hyperammonemia, or “rabbit starvation,” follow [14]. Even at a subclinical level, greater ammonia is a burden on kidney nephrons [15,16]." Mamounis, K.J. The Dangers of Fat Metabolism and PUFA: Why You Don’t Want to be a Fat Burner. Journal of Evolution and Health 2017
55:45 - Kyle's experience on forums ('sometimes the most immature voices are the loudest')
59:20 - Danny thinks "extreme" diets can be motivated by the stress of an unsolved problem
01:00:45 - The long-term physiology associated with fat burning (reduced carbon dioxide)
01:12:10 - Vitamin K is used in proportion to the concentration of carbon dioxide
01:15:40 - Using a preferred nutritional idea to justify any physiological event as positive
01:20:20 - Carbon dioxide regulates the ion and water concentration inside and outside the cell
01:22:28 - Active thyroid hormone (T3), carbon dioxide, temperature, and pulse
01:23:26 - Is low thyroid good for longevity ("rate of living theory")?
01:27:19 - Stress-induced "insulin resistance"
01:32:03 - Low-carb metabolism is a "remix" of starvation and diabetes
01:33:35 - PUFA is a mitochondrial toxin that is stored in a person's tissues
01:36:35 - Are the "essential" fatty acids essential?
01:41:00 - Question: what are practical ways to deplete the body of PUFA?
01:44:29 - Question: what are your views on fasting and autophagy?
01:48:24 - Question: what is your view on hormesis?
01:54:54 - Question: what is your view on dairy?
01:56:53 - Question: how can you reverse insulin resistance?
01:59:56 - Question: what do you think about ketogenic/carnivore success stories?
02:07:00 - Question: what is Kyle's food/supplement routine at the moment?
02:12:33 - Question: what do you think about the sodium/potassium cellular pump idea?
02:19:38 - Super chats