Dr. Becker on Cushing's Disease (Part 1 of 3)

It's a big mistake to wait until every last symptom shows up. By then there's no holding back, and it often takes heavy meds for the rest of your pet's life to control. Too many vets gloss over this key early warning sign. Dogs don't suddenly wake up with this, so this is important.

Cushing’s disease (hyperadrenocorticism) is a condition characterized by an ongoing release of too much cortisol by the adrenal glands.

Cushing’s can produce a variety of diverse symptoms, including increased thirst and urination, hair loss and abdominal weight gain.

Typical Cushing’s disease involves the overproduction of cortisol and can be either adrenal dependent, or more commonly, pituitary dependent; ‘atypical’ Cushing’s involves the overproduction of aldosterone or sex hormones.

Many veterinarians disregard elevations in serum Alkaline Phosphatase (ALP), an enzyme commonly out of range with Cushing’s patients, and a common reason why many cases are diagnosed only after the disease is full-blown.

Cushing’s happens over time, so identifying pre-Cushing’s syndrome as early as possible and reducing the risk for full-blown disease is the best approach.

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