Surprise, Pfizer plans to tackle COVID subvariants, however....what about "original antigenic sin"?

Surprise, Pfizer plans to tackle COVID subvariants, however....
This study shows that any vaccination targetd to other variants doesnt work, orginal antigenic sin?
The study, quietly published earlier this year, bears the somewhat opaque title, “mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron.” https://pubmed.ncbi.nlm.nih.gov/35447072/
It weighs in at a blockbuster 66 authors, including NIAID and NIH scientists.

The researchers compared the rates of waning antibodies in monkeys after being vaccinated with the original mRNA jab to the rate of waning antibodies after vaccination with the variant-specific version. They were surprised to find that there was no additional benefit from the new vaccine version over the original, even though the monkeys in both groups were infected with Omicron and not the original Wuhan strain.

They concluded, “Significant and equivalent control of virus replication in lower airways was observed following either boost.”

So that wasn’t good for business, and explained why we haven’t seen any variant-specific versions. But then things got even more interesting. The 66 authors invoked OAS, original antigenic sin, as a LIKLEY potential explanation for why the newer drugs don’t work against the new variants. Likely.

The observation that boosting with either mRNA-1273 or mRNA-Omicron resulted in the expansion of a similarly high frequency of cross-reactive B cells likely stems from the principle of original antigenic sin, otherwise termed antigenic imprinting, whereby prior immune memory is recalled by a related antigenic encounter.

For new readers, original antigenic sin is a problem observed in some leaky vaccines. What happens is, a person’s immune system gets locked into its original response and never learns any new responses when it encounters variants. In other words, because of the leaky vaccine (the “original sin”), the person’s immune system only makes antibodies to the ORIGINAL viral strain, and never updates its antibodies at all to match new variant types, like an unvaccinated immune system can and will easily do.

In other words, injectees’ immune systems are no longer trainable against the disease.