First published at 13:12 UTC on March 18th, 2022.
Dr. Jason Fung, a nephrologist and author of two previous books, “The Obesity Code” and “The Complete Guide to Fasting,” has now released a third, “The Longevity Solution,” which is the topic of this interview.
While excess protein can activate mT…
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Dr. Jason Fung, a nephrologist and author of two previous books, “The Obesity Code” and “The Complete Guide to Fasting,” has now released a third, “The Longevity Solution,” which is the topic of this interview.
While excess protein can activate mTOR, your protein needs do increase with age, as you need to counteract progressive loss of muscle mass. So, your age really needs to be taken into account.
Protein requirements range from 0.6 grams per kilo of lean body mass in adulthood, up to 2 grams per kilo of lean body mass for young children. The elderly, bodybuilders and endurance athletes typically have higher-than-normal protein requirements for their age group.
It’s important to cycle high and low protein intake. Ideally, combine protein restriction with fasting, followed by increased protein intake on strength training days.
Other nutrients that activate mTOR include branched-chain amino acids, glutamine, methyl folate and vitamin B12; nutrients that inhibit mTOR include curcumin, fisetin and polyphenols such as quercetin, resveratrol and epigallocatechin gallate.
Fasting 16 to 18 hours each day is ideal, as this allows your body to deplete the glycogen stores in your liver to a greater degree and suppress mTOR and activate autophagy better.
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