First published at 22:19 UTC on March 27th, 2024.
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https://www.testosterone.me/what-you-need-to-know-about-testosterone-esters
Testosterone undecanoate. This is an oral form of testosterone. As a rule, oral TRT places more stress on the liver. However, testosterone undecanoate is not a c-17 alpha-alkylated hormone. This allows it to be absorbed through the small intestine directly into the lymphatic system, which places far less stress on the liver.
But there is a disadvantage of testosterone undecanoate: it has a very short shelf life, perhaps only 3 to 4 hours in the body. The result is the need for frequent dosing -- between 3-6 capsules daily. When compared to injectables, this is more expensive. It is sold under the brand names of Andriol, Androxon, Understor, Restandol, and Restinsol. Testosterone undecanoate is not currently available in the U.S.
Testosterone Phenylpropionate. With a release time of one to three weeks, this is considered a slow-acting ester. It is sold under the name brand of Testolent.
Omnadren. This is a mixture of four different testosterone esters: testosterone propionate, phenylpropionate, decanoate, and isocaproate. Omnadren is very similar to Sustanon since it contains both fast-acting and slow-acting esters. Omnadren's injection frequency can range from weekly to monthly. It is quite popular in Europe.
Aqueous testosterone suspension. This is a very brief form of injectable testosterone, as it usually exits the body within a few hours. This explains why it is not the first choice for TRT. Its brand name is “Aquaviron.” This is why most people undergoing testosterone replacement therapy prefer cypionate or enanthate; longer-lasting means fewer injections.
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