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Adam Ruins Rodent Research Models : Part I

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First published at 07:46 UTC on April 7th, 2019.

#adamruinseverything
#animal
#research

IgorandFrankenstein

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Adam ruins everything recently published a video on YouTube titled "The Problem with Lab Mice". This video is riddled with problems and seems to be fueled by a biased liberal agenda. As a result this video is intended to bring some balance back into the topic and directly address some of the claims made that mislead the public and defeat the shows stated purpose. Although biased this video should viewed in the context of the original for reasonable presentation of both arguments.

This video is largely limited to the correction of the key misconceptions :
Why animal models
Why rodents
Filing of paperwork
Expensive drug development
Funding
Genetic similarity
Extreme examples
Human models v animal models
Animal welfare
Human cancer cells and
Animal studies of human disease

First the claims made are corrected to an extent; than the key points are built on. Part II will add details that are glossed over in this video for brevity of a kind.

Links to original video and key articles, suppliers and other material referenced.

The original video of Adams ruins everything : The Problem with Lab Mice.
https://www.youtube.com/watch?v=zvJHq2FJPDM

Genetic Similarity between species
http://www.viralnova.com/genetic-relatives/

Golden age of drug discovery
https://pharmaphorum.com/articles/a_history_of_the_pharmaceutical_industry

Patenting overview
http://www.generalpatent.com/services/patent-licensing

Mouse supplier
https://www.taconic.com/mouse-model/black-6-b6ntac
The specific failed clinical trial article
http://www.nejm.org/doi/full/10.1056/NEJMoa063842#t=article

General articles for reference
http://journals.plos.org/plosclinicaltrials/article?id=10.1371/journal.pctr.0010036

LESS