The Scientific Research Benefits of Testosterone Treatment (TRT)
Testosterone. When most people hear that word, they immediately associate it with masculinity.
Strength...large muscles...aggression...vigor...sexual virility...youth...anti-aging...risk-taking, egocentrism, and longevity.
Scientifically it has been associated with good mental health, muscle development, healthy bones, virility, helping boys become men and high sexual libido. We have several dozen articles on our website here which go over the medical and scientific benefits of testosterone.
All of these traits are, to some degree, accurate and based on many decades or generations of medical and scientific research.
But there is more to the testosterone story – way more when one's testosterone levels are optimized. Not too high, not too low, the "goldy-locks zone" or golden median. For each man or woman, this optimized zone is different, so it's an art and science to find the right balance with testosterone replacement therapy (TRT).
Optimized Testosterone, what typically happens is pretty impressive!
That’s right. Weight-loss, higher sperm count, and a lower risk of developing the dreaded metabolic syndrome are just a few more of testosterone’s benefits.
A recent study concluded that testosterone replacement therapy (TRT) could help you lose weight and keep it off. Let's review the benefits of testosterone.
Hypogonadism (Low Testosterone).
“Obesity is widespread in men with testosterone deficiency (hypogonadism),” said lead study author, Karim Haider, M.D., a urologist and an andrologist who practices medicine in Bremerhaven, Germany.
“Men with hypogonadism and obesity receiving long-term testosterone therapy achieveddoctor, specialist in testosterone benefits progressive and sustained weight loss, while untreated controls gained weight. The favorable decreases in weight and waist circumference may have contributed to the observed reductions in mortality and major cardiovascular events.”
Dr. Haider MD and his fellow researchers are conducting an ongoing study of men with low testosterone levels (“Low-T”). For ten years, they followed 805 patients with hypogonadism who were, on average, aged between their late fifties and mid-sixties.
The 462 (57.4 percent) patients with obesity were given the option to receive testosterone replacement therapy offered by testosterone undecanoate injections (TU) in amounts of 1,000 mg every three months.
For the study group, 273 chose to receive TRT, and the remaining 189 who declined the treatment served as the study’s control group.
For the ten years of the medical research study, the men receiving testosterone dropped 20.3 percent of their baseline body weight (50.5 pounds; 22.9 kg). It was an astonishing result of this clinical trial.
Also, their waist measurements were reduced by 12.5 cm (4.9 inches), and their Body Mass Index (BMI, a measure of body fat that is the ratio of the weight of the body in kilograms to the square of its height in meters) dropped by 7.3 kg/m2, and their waist-to-height ratio decreased by 0.07.
The control group did not experience these beneficial results. This group averaged a 3.9 percent gain in their baseline body weight (3.2 kg; 7.1 pounds), and their waist size expanded by 4.6 cm (1.8 inches).
If that weren’t bad enough, the control group experienced an average increase in BMI of 0.9 kg/m2 and a waist-to-height ratio increase of 0.03.
The importance of these numbers cannot be overemphasized since they play a crucial role in predicting future adverse health issues.
Here’s proof: Throughout the study, 12 (4.4 percent) of the men in the testosterone group died. The control group experienced 57 deaths (30.2 percent), 47 myocardial infarctions or heart attacks (24.9 percent), and 44 strokes (23.3 percent).
The numbers speak for themselves and demonstrate the powerful, life-saving benefits of testosterone. Obesity is thought to be one of the worst killers in the world because it is associated with a full range of cardiovascular disease, cancer, heart attacks, and stroke.
“Our study found long-term testosterone therapy in men with hypogonadism and obesity resulted in significant improvements in measures of body size and composition,” Haider stated. “In addition, testosterone therapy was associated with a reduced risk of death, heart attack, and stroke.
This suggests testosterone levels should be measured in men with obesity, and testosterone therapy should be offered if indicated.
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